Book Now
A couple smiles with their luggage in Florida.

Your (Non-Stop) Ticket to Paradise: Direct Flights to Florida

Dreaming of a Florida getaway, but dread the layovers that often come with getting there? Think of this as your cheat sheet to top Florida destinations with daily non-stop flights from major US cities.

Key West vacation lovers received quite the gift in late 2023: The introduction of more daily direct flights to their beloved eight-square-mile island. In light of so much travel unpredictability in recent years, this is welcome news, promising less travel headaches that often come with a massive layover or a missed connection.

Which made us want to take stock of other top Florida destinations with hassle-free direct flights. Because when getting to the destination is seamless, you kickstart your vacation on a high note. Here’s our roundup of the destinations, the flights, and, once you make your ideal match-up, the Opal Collection resorts or hotels to stay.

Thinking About a Getaway?

Then book a Florida vacation deal at the drop of a hat. Our always-on Opal Moment offer ensures you’re always seeing the best value of the moment at our hotels and resorts in Key West, Sarasota, Clearwater Beach, and The Palm Beaches.
Learn More About Offer


Key West’s diverse and colorful history has molded this southernmost US city into an eclectic array of attractions. Water activities come in the form of snorkeling, parasailing, sunset cruises, deep-sea fishing, and more, while the main artery, Duval Street, pulses with a variety of street cafés, art galleries, world-class restaurants, and nightlife. But one thing is always consistent: At the end of the day, nothing beats the rainbow of colors found in the famous Key West sunset celebration.

Airport: Key West International (EYW)

Airlines with Flights to EYW from the Following Major Cities:

Where to Stay in Key WestThe Capitana Key West | The Laureate Key West | Opal Key Resort & Marina | Sunset Key Cottages (all within four miles of EYW)

The view of downtown Delray Beach.


A warm-weather getaway that has been luring discerning vacationers for more than 125 years, The Palm Beaches in Florida’s East Coast is known as “American’s First Resort Destination” for good reason. A collective of roughly 39 cities and beach towns – including the popular destinations of Delray Beach, Boca Raton, Jupiter, Juno Beach, and West Palm Beach – welcome with scenic sidewalk-lined communities, year-round play on 160 golf courses, high culture in the form of notable museums and performance venues, and delicious places to enjoy Florida’s world-class cuisine. Just looking to live it up at the beach? You’ll find 47 miles of beautiful white-sand coastline here, adjacent to warm ocean waters thanks to a close proximity to the Gulfstream Current.

Airport: Palm Beach International (PBI)

Airlines with Flights from the Following Major Cities:

Where to Stay in Palm Beach County: The Atlantic Suites on The Ave | Delray Sands Resort | Opal Grand Oceanfront Resort & Spa | Jupiter Beach Resort & Spa (all within 20 miles of PBI)


From the Spanish explorers of the 1500s to the Scottish settlers in the late 1800s to the circus followers of the 1920s, a rich, historical past has molded Sarasota into one of the most sought-after cultural destinations in the country. Today, you’ll find neighborhoods lined with colorful homes and a vibrant downtown scene of independent shops, award-winning restaurants, and live music venues, making it an exciting daytime or nighttime destination. Barrier islands, like Longboat, Lido, and Siesta Keys, provide spectacular enclaves of refuge and relaxation that overlook the azure waters of the Gulf of Mexico.

Airport: Sarasota-Bradenton International Airport (SRQ)

Airlines with Flights from the Following Major Cities:

Where to Stay in Sarasota:  Lido Beach Resort | The Resort at Longboat Key Club | Zota Beach Resort (all within 15 miles of SRQ)

A couple rides bikes in Clearwater Beach.


Early 1800’s settlers called this beautiful Gulf Coast enclave “Clear Water Harbor” for the many freshwater springs that bubbled from the banks into the bay. Although these springs are now gone, the name Clearwater stuck – especially since it can just as easily be applied to the clear, azure waters of the Gulf that spill onto soft beaches. Today, Clearwater Beach – lined by a pedestrian-friendly boardwalk with easy access to restaurants, marinas, and one of the most legendary sunsets on the Gulf – has been consistently ranked the best beach in the country by TripAdvisor’s Travelers’ Choice Awards.

Airport: St. Pete–Clearwater International Airport (PIE)

Airlines with Flights from the Following Major Cities:

Where to Stay in Clearwater:  Sandpearl Resort | Opal Sands Resort (both within 14 miles of PIE)

You may also like

Best Florida Vacation Destinations

The quest for the best Florida vacation destinations is a common inquiry – and deeply researched topic – among our guests. So we did the legwork to deliver these curated selections tailored to various travel interests. “Where in Florida should…

Read more
An aerial view of the rooftop bar of Elevate at Opal Grand.

Best Rooftop Bars on the Eastern Seaboard

If you’re looking for rooftop bars along the eastern coast of the US, we have six worthy waterside picks in Opal destinations, from Bar Harbor, Maine, down to Key West, Florida. While you’ll find cool rooftop bars in every major…

Read more
A couple enjoys a wine dinner

5 Activities to Celebrate Leap Year 2024

Leap Year 2024 is upon us. Which means an extra day to dedicate towards enjoying something that you, otherwise, might not have had time for. And we have just the activities and events across Opal destinations to check out on…

Read more
An assortment of empty glassware.

Dry January Tips: How to Master a Month of Mindful Drinking

Considering taking the month-long sobriety challenge known as “Dry January?” Here are a few tips to keep you on the zero-alcohol track – plus, a few mocktail recipes from Opal signature restaurants that are so slakeable, they may just become…

Read more